Article
Leptin levels, leptin receptor gene polymorphisms, and energy metabolism in women.
Obesity research - 1 May 2002
Wauters Machteld, Considine Robert V, Chagnon Monique, Mertens Ilse, Rankinen Tuomo, Bouchard Claude, Van Gaal Luc F
Abstract excerpt
OBJECTIVE: Resting metabolic rate (RMR) is mainly determined by fat-free mass and additionally by age, sex, hormones, and possibly genetic differences. We evaluated whether leptin levels and polymorphisms in the leptin receptor (LEPR) gene were associated with energy expenditure phenotypes. METHODS: RMR, body composition, and leptin levels were measured in 125 overweight and obese women. Three LEPR polymorphisms,...
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