Article
Association of the 103I <i>MC4R</i> allele with decreased body mass in 7937 participants of two population based surveys
1 Apr 2005
Abstract excerpt
BACKGROUND: The melanocortin-4-receptor gene (MC4R) is part of the melanocortinergic pathway that controls energy homeostasis. In a recent meta-analysis, the MC4R V103I (rs2229616) polymorphism was shown to be associated with body weight regulation. Although no functional differences between the isoleucine comprising receptor and the wild type receptor have been detected as yet, this meta-analysis of 14...
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