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Article

Oligomerization state-dependent hyperlipidemic effect of angiopoietin-like protein 4.

Journal of lipid research - 1 Nov 2004

Ge Hongfei, Yang Guoqing, Yu Xinxin, Pourbahrami Tiffany, Li Cai

Abstract excerpt

Angiopoietin-like protein 4 (Angptl4) is the second member of the angiopoietin-like family of proteins previously shown to increase plasma triglyceride (TG) levels in vivo. We recently reported that Angptl4 is a variable-sized oligomer formed by intermolecular disulfide bonds and undergoes regulated proteolytic processing upon secretion. We now show that adenoviral overexpression of Angptl4 potently increases...

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Identifiers

PMID: 15292369
DOI: 10.1194/jlr.M400138-JLR200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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