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Article

Emerging Roles of Angiopoietin-like 4 in Human Cancer

2 Jun 2012

Abstract excerpt

Angiopoietin-like 4 (ANGPTL4) is best known for its role as an adipokine involved in the regulation of lipid and glucose metabolism. The characterization of ANGPTL4 as an adipokine is largely due to our limited understanding of the interaction partners of ANGPTL4 and how ANGPTL4 initiates intracellular signaling. Recent findings have revealed a critical role for ANGPTL4 in cancer growth and progression, anoikis...

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PMID: 22661548
DOI: 10.1158/1541-7786.mcr-11-0519

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