Article
Engineered interphase chromosome loops guide intrachromosomal recombination.
The EMBO journal - 1 Jun 2001
Kostriken R, Wedeen C J
Abstract excerpt
How large-scale topologies regulate interphase chromosome function remains an important question in eukaryotic cell biology. Looped structures are thought to modulate transcription by pairing promoters with distant control elements and to orchestrate intrachromosomal recombination events by pairing appropriate recombination partners. To explore the effects of chromosomal topology on intrachromosomal...
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