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Article

Polymorphisms of the macrophage inhibitory factor and C-reactive protein genes in subjects with Alzheimer's dementia.

Dementia and geriatric cognitive disorders - 1 Jan 2004

Flex Andrea, Pola Roberto, Serricchio Michele, Gaetani Eleonora, Proia Anna S, Di Giorgio Angela, Papaleo Pierangelo, Bernabei Roberto, Pola Paolo

Abstract excerpt

Neuroinflammation is a central feature of Alzheimer's disease (AD). C-reactive protein (CRP) is a key molecule of the acute phase of inflammation that has been localized in the two characteristic lesions of AD brain, senile plaque and neurofibrillary tangles. On the other hand, the macrophage migration inhibitory factor (MIF) is a cytokine with multiple biological activities, including the ability to act as...

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PMID: 15286457
DOI: 10.1159/000080026

Genes

CRP
MIF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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