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Article

Association of anti-inflammatory cytokine IL10 polymorphisms with motoric cognitive risk syndrome in an Ashkenazi Jewish population.

Neurobiology of aging - 1 Oct 2017

Sathyan Sanish, Barzilai Nir, Atzmon Gil, Milman Sofiya, Ayers Emmeline, Verghese Joe

Abstract excerpt

Motoric cognitive risk (MCR) syndrome is a newly described predementia syndrome characterized by the presence of cognitive complaints and slow gait, which is associated with increased risk of conversion to dementia. The underlying biological mechanisms for MCR have not yet been established. Neuroinflammation mediated through cytokines plays a pivotal role in the pathogenesis of dementia. Hence, our objective was...

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Identifiers

PMID: 28705468
DOI: 10.1016/j.neurobiolaging.2017.06.006
PMCID: PMC5581722

Genes

CRP
IFNG
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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