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Article

Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism and risk of Alzheimer's disease in Italians.

Experimental gerontology - 1 Aug 2004

Pola Roberto, Flex Andrea, Gaetani Eleonora, Proia Anna S, Papaleo Pierangelo, Di Giorgio Angela, Straface Giuseppe, Pecorini Giovanni, Serricchio Michele, Pola Paolo

Abstract excerpt

Monocyte chemoattractant protein-1 (MCP-1) is a key molecule for monocyte chemotaxis and tissue extravasation and for the modulation of leukocyte function during inflammation. Upregulation of MCP-1 may occur in the brain of subjects affected by Alzheimer's disease (AD) and MCP-1 levels in plasma and cerebrospinal fluid have been proposed as biological markers for the inflammatory process that accompanies AD...

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Identifiers

PMID: 15288699
DOI: 10.1016/j.exger.2004.05.001

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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