Article
Prolactin levels in antipsychotic treatment of patients with schizophrenia carrying the DRD2*A1 allele.
The British journal of psychiatry : the journal of mental science - 1 Aug 2004
Young Ross McD, Lawford Bruce R, Barnes Mark, Burton Simon C, Ritchie Terry, Ward Warren K, Noble Ernest P
Abstract excerpt
BACKGROUND: Hyperprolactinaemia induced by D(2) dopamine receptor antagonist antipsychotic medication can result in significant health problems. AIMS: To examine the role of DRD2 polymorphism on prolactin levels in patients treated with antipsychotic medication. METHOD: Antipsychotic drugs with different degrees of D(2) receptor binding were given to 144 patients with schizophrenia. Serum prolactin levels were...
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