Article
Variants of the dopamine D2 receptor gene and risperidone-induced hyperprolactinemia in children and adolescents.
Pharmacogenetics and genomics - 1 May 2009
Calarge Chadi A, Ellingrod Vicki L, Acion Laura, Miller Del D, Moline Jessica, Tansey Michael J, Schlechte Janet A
Abstract excerpt
OBJECTIVE: To investigate the association between hyperprolactinemia and variants of the dopamine D2 receptor (DRD2) gene in children and adolescents in long-term treatment with risperidone. METHODS: Medically healthy 7 to 17-year-old patients chronically treated with risperidone but receiving no other antipsychotics were recruited in a cross-sectional study. Four DRD2 variants were genotyped and prolactin...
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