Article
Taq1A polymorphism in the dopamine D2 receptor gene as a predictor of clinical response to aripiprazole.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Dec 2008
Kwon Jun Soo, Kim Euitae, Kang Do-Hyung, Choi Jung Seok, Yu Kyung-Sang, Jang In-Jin, Shin Sang-Goo
Abstract excerpt
We investigated whether the clinical response to aripiprazole differed according to the Taq1A polymorphism in the dopamine D2 receptor (DRD2) gene. In this 26-week, prospective, open-label, double-blind, parallel-group study, 90 patients with schizophrenia, schizoaffective disorder, or schizophreniform disorder were recruited and divided into two groups according to their DRD2 genotype (A1A1, n=14; A1A2+A2A2,...
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