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Article

Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia.

Leukemia - 1 Sept 2004

Montpetit A, Larose J, Boily G, Langlois S, Trudel N, Sinnett D

Abstract excerpt

Allelic losses on chromosome 12p12-13 are associated with childhood acute lymphoblastic leukemia (ALL) and several solid neoplasias, suggesting the presence of a tumor suppressor locus. The recent construction of a transcription map of this locus has enabled the identification of eight genes, of which five were previously known: ETV6, BCL-G, LRP6, MKP-7, and CDKN1B. The three other candidate genes, LOH12CR1,...

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Share to Chromosomes, Human, Pair 12
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Polymorphism, Single-Stranded Conformational

Share to Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to RNA, Neoplasm

Share to Translocation, Genetic

Source

Identifiers

PMID: 15284860
DOI: 10.1038/sj.leu.2403441

Genes

ETV6
CDKN1B
LRP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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