Article
Abnormalities of the long arm of chromosome 6 in childhood acute lymphoblastic leukemia.
Blood - 15 Oct 1990
Hayashi Y, Raimondi S C, Look A T, Behm F G, Kitchingman G R, Pui C H, Rivera G K, Williams D L
Abstract excerpt
To determine the biologic significance of the structural rearrangements of the long arm of chromosome 6(6q) in acute lymphoblastic leukemia (ALL) at diagnosis, we studied 412 consecutive children whose leukemic cell chromosomes had been completely banded and identified 45 (11%) children with this abnormality. The 45 cases were divided into del(6q) only (n = 11), del(6q) and numerical abnormalities (n = 4),...
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