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Article

Deletion of chromosomal region 13q14.3 in childhood acute lymphoblastic leukemia.

Leukemia - 1 Mar 2001

Cavé H, Avet-Loiseau H, Devaux I, Rondeau G, Boutard P, Lebrun E, Méchinaud F, Vilmer E, Grandchamp B

Abstract excerpt

Deletion of the 13q14 chromosomal region is frequent in B cell chronic lymphocytic leukemia (B-CLL) and is believed to inactivate a tumor supressor gene (TSG) next to RB1. We studied microsatellite markers spanning the 13q14 chromosomal region in 138 children with acute lymphoblastic leukemia (ALL). Allelic loss was demonstrated in six cases (4.3%). Deletion did not include RB1 in two cases. In five patients, the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11237059
DOI: 10.1038/sj.leu.2402052

Genes

RB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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