Article
Skeletal muscle calcineurin: influence of phenotype adaptation and atrophy.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Apr 2001
Spangenburg E E, Williams J H, Roy R R, Talmadge R J
Abstract excerpt
Calcineurin (CaN) has been implicated as a signaling molecule that can transduce physiological stimuli (e.g., contractile activity) into molecular signals that initiate slow-fiber phenotypic gene expression and muscle growth. To determine the influence of muscle phenotype and atrophy on CaN levels in muscle, the levels of soluble CaN in rat muscles of varying phenotype, as assessed by myosin heavy chain...
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