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Article

Identification of variants in cyclin D1 ( CCND1) and B-Cell CLL/lymphoma 2 ( BCL2).

Journal of human genetics - 1 Jan 2004

Park Byung Lae, Kim Lyoung Hyo, Cheong Hyun Sub, Cho Hye Young, Kim Eun Mi, Shin Hyoung Doo, Kim Yong-Sun, Lee Chaeyoung

Abstract excerpt

CCND1 is an important cell-cycle regulatory protein associated with cell proliferation, poor prognosis and recurrence in cancer, while BCL2 is an important anti-apoptotic protein that plays a vital role in the regulation of the life span by controlling the rate of apoptosis. Recent studies have shown that CCND1 and BCL2 may be responsible for the body mass and the regulation of various metabolic processes. In an...

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Source

Identifiers

PMID: 15278764
DOI: 10.1007/s10038-004-0173-0

Genes

BCL2
CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of variants in cyclin D1 ( CCND1) and B-Cell CLL/lymphoma 2 ( BCL2).PMID 15278764Read ↗

Association of Genetic Variants at the CDKN1B and CCND2 Loci Encoding p27Kip1 and Cyclin D2 Cell Cycle Regulators with Susceptibility and Clinical Course of Chronic Lymphocytic Leukemia.Semantic proximity Read ↗

Association of CCND1 Gene c.870G>A Polymorphism with Breast Cancer Risk: A Case-ControlStudy and a Meta-Analysis.Semantic proximity Read ↗

Genetic polymorphisms in cell cycle regulatory genes CCND1 and CDK4 are associated with susceptibility to breast cancer.Semantic proximity Read ↗

Computational analysis of Cyclin D1 gene SNPs and association with breast cancer.Semantic proximity Read ↗

CCND1 and CDKN1B polymorphisms and risk of breast cancer.Semantic proximity Read ↗

CCND1 G870A polymorphism contributes to breast cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Association of cyclin D1 genotype with breast cancer risk and survival.Semantic proximity Read ↗

Cyclin D1 splice variant and risk for non-Hodgkin lymphoma.Semantic proximity Read ↗

Altered expression and mutations in cell cycle genes CCND1, CDK4, CDKN2B and TP53 are associated with Pakistani breast cancer patients.Semantic proximity Read ↗

Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.Semantic proximity Read ↗

Genetic polymorphisms in cyclin D1 are associated with risk of renal cell cancer in the Chinese populationSemantic proximity Read ↗

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