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Article

CCND1 G870A polymorphism contributes to breast cancer susceptibility: a meta-analysis.

Breast cancer research and treatment - 1 Aug 2009

Lu Cheng, Dong Jing, Ma Hongxia, Jin Guangfu, Hu Zhibin, Peng Yuzhu, Guo Xirong, Wang Xinru, Shen Hongbing

Abstract excerpt

Cyclin D1 (CCND1), a key cell cycle regulatory protein that governs the cell cycle progression from G1 to S phase, can promote cell proliferation or induce growth arrest and apoptosis. Since the identification of a well-characterized functional polymorphism, G870A in exon 4 of CCND1, several molecular epidemiological studies were conducted in recent years to evaluate the association between G870A and breast...

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Source

Identifiers

PMID: 18819000
DOI: 10.1007/s10549-008-0195-y

Genes

CCND1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

CCND1 G870A polymorphism contributes to breast cancer susceptibility: a meta-analysis.PMID 18819000Read ↗

Cyclin D1 G870A polymorphism and breast cancer risk: a meta-analysis comprising 9,911 cases and 11,171 controls.Semantic proximity Read ↗

Association of CCND1 Gene c.870G>A Polymorphism with Breast Cancer Risk: A Case-ControlStudy and a Meta-Analysis.Semantic proximity Read ↗

Specific CCND1 G870A alleles associated with breast cancer susceptibility: a meta-analysis of 5,528 cases and 5,353 controls.Semantic proximity Read ↗

Association between cyclin D1 (CCND1) G870A polymorphism and gastric cancer risk: a meta-analysis.Semantic proximity Read ↗

Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis.Semantic proximity Read ↗

The association between CCND1 G870A polymorphism and colorectal cancer risk: A meta-analysis.Semantic proximity Read ↗

CCND1 G870A polymorphism and cervical cancer risk: a case-control study and meta-analysis.Semantic proximity Read ↗

Cyclin D1 (CCND1) G870A polymorphisms and cervical cancer susceptibility: a meta-analysis based on ten case-control studies.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism contributes to colorectal cancer susceptibility: evidence from a systematic review of 22 case-control studies.Semantic proximity Read ↗

Breast cancer and cyclin D1 gene polymorphism in Turkish women.Semantic proximity Read ↗

The CCND1 G870A polymorphism and susceptibility to bladder cancer.Semantic proximity Read ↗

Cyclin D1 G870A polymorphism is associated with risk and clinicopathologic characteristics of bladder cancer.Semantic proximity Read ↗

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