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CCND1 and CDKN1B polymorphisms and risk of breast cancer.

Anticancer research - 1 Jul 2010

Canbay Emel, Eraltan Ilhan Yaylim, Cercel Ali, Isbir Turgay, Gazioglu Ertugrul, Aydogan Fatih, Cacina Canan, Cengiz Ali, Ferahman Mehmet, Zengin Emel, Unal Hilal

Abstract excerpt

BACKGROUND AND OBJECTIVES: Previous studies have shown alterations in the cell cycle regulatory proteins in breast carcinomas. However, the results of these studies remain controversial. Cyclin D1 (CCND1) and p27(KIP1) (CDKN1B) are two essential regulators of cell cycle progression. This study aimed to investigate the associations of CCND1 A870G and CDKN1B C79T polymorphisms with breast cancer risk. PATIENTS AND...

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Alleles
Breast Neoplasms
Cyclin D1
Cyclin-Dependent Kinase Inhibitor p27
Intracellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Staging

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 20683061

Genes

CCND1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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