Article
Association analysis of C6 genetic variations and aspirin hypersensitivity in Korean asthmatic patients.
Human immunology - 1 Oct 2011
Pasaje Charisse Flerida A, Bae Joon Seol, Park Byung-Lae, Cheong Hyun Sub, Jang An-Soo, Uh Soo-Taek, Kim Mi-Kyeong, Koh In Song, Kim Jeong-Hyun, Park Tae-Joon, Lee Jin-Sol, Kim Yongha, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
There has been increasing evidence that genetic mechanisms contribute to the development of aspirin-intolerant asthma (AIA), a life-threatening disease. The complement component (C6) is a constituent of a biochemical cascade that has been implicated in airway epithelial damage and nasal polyposis...
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