Article
Association between PLA2 gene polymorphisms and treatment response to antipsychotic medications: A study of antipsychotic-naïve first-episode psychosis patients and nonadherent chronic psychosis patients.
Prostaglandins, leukotrienes, and essential fatty acids - 1 Jul 2023
Nadalin Sergej, Zatković Lena, Peitl Vjekoslav, Karlović Dalibor, Vidrih Branka, Puljić Antonia, Pavlić Sanja Dević, Buretić-Tomljanović Alena
Abstract excerpt
Here we investigated whether antipsychotic treatment was influenced by three polymorphisms: rs10798059 (BanI) in the phospholipase A2 (PLA2)G4A gene, rs4375 in PLA2G6, and rs1549637 in PLA2G4C. A total of 186 antipsychotic-naïve first-episode psychosis patients or nonadherent chronic psychosis individuals (99 males and 87 females) were genotyped by polymerase chain reaction analysis/restriction fragment length...
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