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Article

Association between polymorphisms of arachidonate 12-lipoxygenase (ALOX12) and schizophrenia in a Korean population.

Behavioral and brain functions : BBF - 14 Jul 2010

Kim Tae, Kim Hak-Jae, Park Jin Kyung, Kim Jong Woo, Chung Joo-Ho

Abstract excerpt

Arachidonic acid (AA), an essential polyunsaturated fatty acid, is one of the major components of neural membranes, which show an altered phospholipid composition in schizophrenia. Arachidonate 12-lipoxygenase (ALOX12), an important enzyme, metabolizes AA to 12-HPETE, which affects catecholamine synthesis. However, research has yet to show the genetic association between ALOX12 and schizophrenia. Therefore, we...

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Source

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Identifiers

PMID: 20626912
DOI: 10.1186/1744-9081-6-44
PMCID: PMC2909989

Genes

ALOX12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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