Article
Antioxidant role of human haptoglobin.
Proteomics - 1 Aug 2004
Tseng Chi Feng, Lin Chia Ching, Huang Hsing Yi, Liu Huei Chun, Mao Simon J T
Abstract excerpt
Human plasma haptoglobin (Hp) is classified according to three phenotypes: Hp 1-1, 2-1, and 2-2 attributed by their two common alleles 1 and 2. Clinically, the 2-2 phenotype is associated with the risk of cardiovascular diseases and diabetes mellitus in patients. In this study, we demonstrate that Hp is an extremely potent antioxidant, which directly protects low density lipoprotein from Cu(2+)-induced oxidation....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.