Article
Structure-function analysis of the antioxidant properties of haptoglobin.
Blood - 15 Dec 2001
Melamed-Frank M, Lache O, Enav B I, Szafranek T, Levy N S, Ricklis R M, Levy A P
Abstract excerpt
Haptoglobin serves as an antioxidant by virtue of its ability to prevent hemoglobin-driven oxidative tissue damage. It was recently demonstrated that an allelic polymorphism in the haptoglobin gene is predictive of the risk for numerous microvascular and macrovascular diabetic complications. Because these complications are attributed in large part to an increase in oxidative stress, a study was conducted to...
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