Accuracy of cDNA microarray methods to detect small gene expression changes induced by neuregulin on breast epithelial cells

Abstract excerpt

BACKGROUND: cDNA microarrays are a powerful means to screen for biologically relevant gene expression changes, but are often limited by their ability to detect small changes accurately due to "noise" from random and systematic errors. While experimental designs and statistical analysis methods have been proposed to reduce these errors, few studies have tested their accuracy and ability to identify small, but...

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