Article
Normalization of microarray data using a spatial mixed model analysis which includes splines.
Bioinformatics (Oxford, England) - 22 Nov 2004
Baird David, Johnstone Peter, Wilson Theresa
Abstract excerpt
MOTIVATION: Microarray experiments with thousands of genes on a slide and multiple slides used in any experimental set represent a large body of data with many sources of variation. The identification of such sources of variation within microarray experimental sets is critical for correct deciphering of desired gene expression differences. RESULTS: We describe new methods for the normalization using spatial mixed...
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