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Article

Use of within-array replicate spots for assessing differential expression in microarray experiments.

Bioinformatics (Oxford, England) - 1 May 2005

Smyth Gordon K, Michaud Joëlle, Scott Hamish S

Abstract excerpt

MOTIVATION: Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the resulting information. The usual practice is to average the duplicate or triplicate results for each probe before assessing differential expression. This results in the loss of valuable information about genewise variability. RESULTS: A...

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PMID: 15657102
DOI: 10.1093/bioinformatics/bti270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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