Article
Which is better for cDNA-microarray-based classification: ratios or direct intensities.
Bioinformatics (Oxford, England) - 1 Nov 2004
Attoor Sanju, Dougherty Edward R, Chen Yidong, Bittner Michael L, Trent Jeffrey M
Abstract excerpt
MOTIVATION: There are two general methods for making gene-expression microarrays: one is to hybridize a single test set of labeled targets to the probe, and measure the background-subtracted intensity at each probe site; the other is to hybridize both a test and a reference set of differentially labeled targets to a single detector array, and measure the ratio of the background-subtracted intensities at each...
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