Article
Replication, variation and normalisation in microarray experiments.
Applied bioinformatics - 1 Jan 2005
Altman Naomi
Abstract excerpt
INTRODUCTION: Microarray experiments often have complex designs that include sample pooling, biological and technical replication, sample pairing and dye-swapping. This article demonstrates how statistical modelling can illuminate issues in the design and analysis of microarray experiments, and this information can then be used to plan effective studies. METHODS: A very detailed statistical model for microarray...
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