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Article

Expression of the LspA1 and LspA2 proteins by Haemophilus ducreyi is required for virulence in human volunteers.

Infection and immunity - 1 Aug 2004

Janowicz Diane M, Fortney Kate R, Katz Barry P, Latimer Jo L, Deng Kaiping, Hansen Eric J, Spinola Stanley M

Abstract excerpt

Haemophilus ducreyi colocalizes with polymorphonuclear leukocytes and macrophages and evades phagocytosis during experimental infection of human volunteers. H. ducreyi contains two genes, lspA1 and lspA2, which encode predicted proteins of 456 and 543 kDa, respectively. Compared to its wild-type parent, an lspA1 lspA2 double mutant does not inhibit phagocytosis by macrophage and myelocytic cell lines in vitro and...

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Identifiers

PMID: 15271912
DOI: 10.1128/IAI.72.8.4528-4533.2004
PMCID: PMC470669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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