Article
A DltA mutant of Haemophilus ducreyi Is partially attenuated in its ability to cause pustules in human volunteers.
Infection and immunity - 1 Feb 2006
Janowicz Diane, Leduc Isabelle, Fortney Kate R, Katz Barry P, Elkins Christopher, Spinola Stanley M
Abstract excerpt
Haemophilus ducreyi produces two outer membrane proteins, called DltA (H. ducreyi lectin A) and DsrA (H. ducreyi serum resistance A), that contribute to the ability of the organism to evade complement-mediated serum killing. In contrast to their isogenic parent strain, 35000HP, the DsrA mutant FX517 exhibits 0% survival in 50% normal human serum and the DltA mutant FX533 exhibits 23% survival. Compared to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.