Article
A fibrinogen-binding lipoprotein contributes to the virulence of Haemophilus ducreyi in humans.
The Journal of infectious diseases - 1 Mar 2009
Bauer Margaret E, Townsend Carisa A, Doster Ryan S, Fortney Kate R, Zwickl Beth W, Katz Barry P, Spinola Stanley M, Janowicz Diane M
Abstract excerpt
A gene expression study of Haemophilus ducreyi identified the hypothetical lipoprotein HD0192, renamed here "fibrinogen binder A" (FgbA), as being preferentially expressed in vivo. To test the role played by fgbA in virulence, an isogenic fgbA mutant (35000HPfgbA) was constructed using H. ducreyi...
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