Article
STK15 polymorphisms and association with risk of invasive ovarian cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2004
Dicioccio Richard A, Song Honglin, Waterfall Christy, Kimura Makoto T, Nagase Hiroki, McGuire Valerie, Hogdall Estrid, Shah Mitul N, Luben Robert N, Easton Douglas F, Jacobs Ian J, Ponder Bruce A J, Whittemore Alice S, Gayther Simon A, Pharoah Paul D P, Kruger-Kjaer Susan
Abstract excerpt
STK15 is a putative oncogene that codes for a centrosome-associated, serine/threonine kinase, the normal function of which is to ensure accurate segregation of chromosomes during mitosis. Amplification of STK15 has been reported in ovarian tumors, suggesting a role in ovarian cancer pathology. ST...
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