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Article

The 811 C/T polymorphism in the 3' untranslated region of the selenoprotein 15-kDa (Sep15) gene and breast cancer in Caucasian women.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2016

Watrowski Rafał, Castillo-Tong Dan Cacsire, Fabjani Gerhild, Schuster Eva, Fischer Michael, Zeillinger Robert

Abstract excerpt

The 15-kDa selenoprotein (Sep15) is a selenocysteine-containing oxidoreductase in the endoplasmic reticulum that participates in disulfide-bond formation and protein folding control. The 3'-untranslated region (3'-UTR) contains two exclusively linked, polymorphic sites at positions 811 (C/T) and 1125 (G/A), which result in two functional haplotypes: 811C/1125G or 811T/1125A. The 811T/1125A variant occurs...

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PMID: 26264612
DOI: 10.1007/s13277-015-3847-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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