Article
A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transport.
Molecular biology of the cell - 1 Oct 2004
Hou Yuqing, Pazour Gregory J, Witman George B
Abstract excerpt
Intraflagellar transport (IFT), the bidirectional movement of particles along flagella, is essential for flagellar assembly. The motor for retrograde IFT in Chlamydomonas is cytoplasmic dynein 1b, which contains the dynein heavy chain DHC1b and the light intermediate chain (LIC) D1bLIC. To investigate a possible role for the LIC in IFT, we identified a d1blic mutant. DHC1b is reduced in the mutant, indicating...
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