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Article

The Chlamydomonas IDA7 locus encodes a 140-kDa dynein intermediate chain required to assemble the I1 inner arm complex.

Molecular biology of the cell - 1 Dec 1998

Perrone C A, Yang P, O'Toole E, Sale W S, Porter M E

Abstract excerpt

To identify new loci that are involved in the assembly and targeting of dynein complexes, we have screened a collection of motility mutants that were generated by insertional mutagenesis. One such mutant, 5B10, lacks the inner arm isoform known as the I1 complex. This isoform is located proximal to the first radial spoke in each 96-nm axoneme repeat and is an important target for the regulation of flagellar...

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Identifiers

PMID: 9843574
DOI: 10.1091/mbc.9.12.3351
PMCID: PMC25636

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