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Article

Nucleolar localization of the human telomeric repeat binding factor 2 (TRF2)

21 Jul 2004

Abstract excerpt

The telomeric repeat binding factor 2 (TRF2) specifically recognizes TTAGGG tandem repeats at chromosomal ends. Unexpectedly immunofluorescence studies revealed a prominent nucleolar localization of TRF2 in human cells, which appeared as discrete dots with sizes similar to those present in the nucleoplasm. The TRF2 dots did not overlap with dots stemming from the upstream binding factor (UBF) or the B23 protein....

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PMID: 15265990
DOI: 10.1242/jcs.01249

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