Article
Cell Cycle-dependent Recruitment of Telomerase RNA and Cajal Bodies to Human Telomeres
30 Nov 2005
Abstract excerpt
Telomerase is a ribonucleoprotein enzyme that counteracts replicative telomere erosion by adding telomeric sequence repeats onto chromosome ends. Despite its well-established role in telomere synthesis, telomerase has not yet been detected at telomeres. The RNA component of human telomerase (hTR) resides in the nucleoplasmic Cajal bodies (CBs) of interphase cancer cells. Here, in situ hybridization demonstrates...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
