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Article

IFN-α Subtypes Differentially Affect Human T Cell Motility

1 Aug 2004

Abstract excerpt

The type I IFN family includes 14 closely related antiviral cytokines that are produced in response to viral infections. They bind to a common receptor, and have qualitatively similar biological activities. The physiological relevance of this redundancy is still unclear. In this study, we analyzed and compared the effects of two potent antiviral type I IFNs, IFN-alpha 2 and IFN-alpha 8, on the motility of various...

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Share to Chemokine receptors and signaling
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PMID: 15265895
DOI: 10.4049/jimmunol.173.3.1663

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