Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic Cells

1 Nov 2003

Abstract excerpt

Type I IFNs (IFN-alphabeta) constitute a family of cytokines that have important antiviral and immunoregulatory properties and have been successfully used in the treatment of a wide variety of diseases. There are 12 functional human IFN-alpha subtypes and one IFN-beta subtype that signal through the common cell surface IFN-alphabetaR. To date, virtually no information is available on the specificity of IFN-alpha...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14607926
DOI: 10.4049/jimmunol.171.10.5255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic CellsPMID 14607926Read ↗

Expression profiles of human interferon‐alpha and interferon‐lambda subtypes are ligand‐ and cell‐dependentSemantic proximity Read ↗

Type I IFN family members: similarity, differences and interaction.Semantic proximity Read ↗

Heterogeneity and functions of the 13 IFN‐α subtypes – lucky for some?Semantic proximity Read ↗

Dissecting type I and II interferon impacts on human immune cells in disease by a cell type-specific interferon response atlasSemantic proximity Read ↗

Shared and Unique Features of Human Interferon-Beta and Interferon-Alpha SubtypesSemantic proximity Read ↗

Dissecting Interferon-Induced Transcriptional Programs in Human Peripheral Blood CellsSemantic proximity Read ↗

IFN-α and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T cellsSemantic proximity Read ↗

Single-cell analysis of signalling and transcriptional responses to type I interferonsSemantic proximity Read ↗

Differential interferon-α subtype immune signatures suppress SARS-CoV-2 infectionSemantic proximity Read ↗

Interferon-Beta Induces Distinct Gene Expression Response Patterns in Human Monocytes versus T cellsSemantic proximity Read ↗

Monocytes differentiated into macrophages and dendritic cells in the presence of human IFN-λ3 or IFN-λ4 show distinct phenotypes.Semantic proximity Read ↗

Analysis of interferon-λ1 gene activation and functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.