Article
Rho-mediated assembly of stress fibers is differentially regulated in corneal fibroblasts and myofibroblasts.
Experimental cell research - 15 Aug 2004
Anderson Susan, DiCesare Lisa, Tan Ivan, Leung Thomas, SundarRaj Nirmala
Abstract excerpt
Corneal keratocytes (stromal cells) are activated to fibroblasts and myofibroblasts during wound healing. Myofibroblast transdifferentiation is accompanied by the expression of alpha-smooth muscle actin (alpha-SMA) and the assembly of a robust stress fiber network and larger focal adhesions (FAs). The regulation of the assembly of stress fibers was evaluated in cultured corneal fibroblast and myofibroblast...
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