Article
The association between transforming growth factor-beta gene promoter C-509T polymorphism and Chinese children with Henoch-Schönlein purpura.
Pediatric nephrology (Berlin, Germany) - 1 Sept 2004
Yang Yao-Hsu, Lai Huey-Jen, Kao Cheng-Kai, Lin Yu-Tsan, Chiang Bor-Luen
Abstract excerpt
Many cytokines, including transforming growth factor-beta (TGF-beta) and tumor necrosis factor-alpha (TNF-alpha), are involved in the inflammatory process of Henoch-Schönlein purpura (HSP). The objective of this study was to investigate whether TGF-beta C-509T and TNF-alpha G-308A polymorphisms are associated with childhood HSP. The loci of interest were amplified from genomic DNA using specific primers and...
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