Article
The association between genetic variation in interleukin-10 gene and susceptibility to Henoch-Schönlein purpura in Chinese children.
Clinical rheumatology - 1 Dec 2017
Xu Hui, Jiang Guizhen, Shen Hongqiang, Pan Yanxiang, Zhang Junfeng, Li Wei, Mao Jianhua
Abstract excerpt
Interleukin-10 (IL-10), one of the anti-inflammatory cytokines, plays a major role in the pathogenesis of Henoch-Schönlein purpura (HSP). In present study, we investigated the association between genetic variation in IL-10 gene and susceptibility to HSP in a Chinese childhood population. Considering the overlapping clinical manifestations during the course of disease, the relation between IL-10 gene polymorphisms...
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