Article
Heat shock protein 70-2 and tumor necrosis factor-α gene polymorphisms in Chinese children with Henoch-Schönlein purpura.
World journal of pediatrics : WJP - 1 Feb 2016
Ding Gui-Xia, Wang Chen-Hu, Che Ruo-Chen, Guan Wan-Zhen, Yuan Yang-Gang, Su Min, Zhang Ai-Hua, Huang Song-Ming
Abstract excerpt
BACKGROUND: Henoch-Schönlein purpura (HSP) or IgA-associated vasculitis is related to immune disturbances. Polymorphisms of the heat shock protein 70-2 gene (HSP70-2) and the tumor necrosis factor-a gene (TNF-α) are known to be associated with immune diseases. The purpose of this study was to investigate the likely association of HSP70-2 (+1267A/G) and TNF-α (+308A/G) gene polymorphisms with HSP in children....
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