Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.

Microbiology (Reading, England) - 1 Jul 2004

Miyazaki Takashi, Miyazaki Junichi, Yamane Hisakazu, Nishiyama Makoto

Abstract excerpt

The extremely thermophilic bacterium Thermus thermophilus HB27 synthesizes lysine through alpha-aminoadipate (AAA). In this study, a T. thermophilus gene encoding the enzyme that catalyses transamination of AAA was cloned as a mammalian kynurenine/AAA aminotransferase (Kat2) gene homologue. A T. thermophilus mutant with disruption of the Kat2 homologue required a longer lag phase for growth and showed slower...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cloning, Molecular
Share to Culture Media
Share to Hot Temperature

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kinetics

Share to Recombinant Proteins

Share to Sequence Analysis, DNA

Share to Thermus thermophilus

Share to Transaminases

Source

Identifiers

PMID: 15256574
DOI: 10.1099/mic.0.27037-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.PMID 15256574Read ↗

Lysine is synthesized through the alpha-aminoadipate pathway in Thermus thermophilus.Semantic proximity Read ↗

An ornithine ω-aminotransferase required for growth in the absence of exogenous proline in the archaeon Thermococcus kodakarensis.Semantic proximity Read ↗

Aspartate kinase-independent lysine synthesis in an extremely thermophilic bacterium, Thermus thermophilus: lysine is synthesized via alpha-aminoadipic acid not via diaminopimelic acid.Semantic proximity Read ↗

Engineering Tk1656, a highly active l-asparaginase from Thermococcus kodakarensis, for enhanced activity and stability.Semantic proximity Read ↗

Kynurenine aminotransferase activity of Aro8/Aro9 engage tryptophan degradation by producing kynurenic acid in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mammalian aspartate aminotransferase isozymes. From DNA to protein.Semantic proximity Read ↗

Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine.Semantic proximity Read ↗

Identification of a novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: <i>Pseudomonas aeruginosa</i> LdcASemantic proximity Read ↗

Mutational insights into human kynurenine aminotransferase 1: modulation of transamination and β-elimination activities across diverse substratesSemantic proximity Read ↗

Mutational insights into human kynurenine aminotransferase 1: modulation of transamination and β-elimination activities across diverse substrates.Semantic proximity Read ↗

Discovery of the 1-naphthylamine biodegradation pathway reveals an enzyme that catalyzes 1-naphthylamine glutamylationSemantic proximity Read ↗

Metabolism Dealing with Thermal Degradation of NAD+ in the Hyperthermophilic Archaeon Thermococcus kodakarensis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.