Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine.

The Journal of biological chemistry - 2 Mar 2012

Veiga-da-Cunha Maria, Hadi Farah, Balligand Thomas, Stroobant Vincent, Van Schaftingen Emile

Abstract excerpt

The purpose of the present work was to identify the catalytic activity of AGXT2L1 and AGXT2L2, two closely related, putative pyridoxal-phosphate-dependent enzymes encoded by vertebrate genomes. The existence of bacterial homologues (40-50% identity with AGXT2L1 and AGXT2L2) forming bi- or tri-functional proteins with a putative kinase belonging to the family of aminoglycoside phosphotransferases suggested that...

Topics

Animals
Bacteria
Bacterial Proteins
Bipolar Disorder
Ethanolamines
Genome, Bacterial
Genome, Human
Humans
Hydroxylysine
Mutation
Schizophrenia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Amino Acid

Transaminases

Source

Open in PubMed Open full text

Identifiers

PMID: 22241472
DOI: 10.1074/jbc.M111.323485
PMCID: PMC3293546

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine.PMID 22241472Read ↗

Mutations in the AGXT2L2 gene cause phosphohydroxylysinuria.Semantic proximity Read ↗

The role of transglutaminase-2 and its substrates in human diseases.Semantic proximity Read ↗

Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a unique member of the 2H phosphoesterase family.Semantic proximity Read ↗

alpha-Aminoadipate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus.Semantic proximity Read ↗

Recognition of arylsulfatase A and B by the UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-phosphotransferase.Semantic proximity Read ↗

Evidence that human histidine triad nucleotide binding protein 3 (Hint3) is a distinct branch of the histidine triad (HIT) superfamily.Semantic proximity Read ↗

A Chemical Mechanistic Path Leads the Way to Cellular ArgpyrimidineSemantic proximity Read ↗

The crystal structure of Aquifex aeolicus prephenate dehydrogenase reveals the mode of tyrosine inhibition.Semantic proximity Read ↗

Function discovery and structural characterization of a methylphosphonate esterase.Semantic proximity Read ↗

A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase.Semantic proximity Read ↗

Lysine metabolism in higher plants.Semantic proximity Read ↗

Identification and elucidation of in vivo function of two alanine racemases from Pseudomonas putida KT2440.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.