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Identification of a novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: <i>Pseudomonas aeruginosa</i> LdcA

2018-04-25

Abstract excerpt

<h4>Summary</h4> Polyamines are small amino-acid derived polycations capable of binding negatively charged macromolecules. Bacterial polyamines are structurally and functionally diverse, and are mainly produced biosynthetically by PLP-dependent amino acid decarboxylases referred to as LAOdcs (Lysine-Arginine-Ornithine decarboxylases). In a phylogenetically limited group of bacteria, LAOdcs are also induced in res...

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Literature Corpus work
54182f54-a435-5c65-b07a-7913a71bb75e
DOI
10.1101/308080
Open publication

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