Article
Normal mammary gland growth and lactation capacity in pregnant relaxin-deficient mice.
Reproduction, fertility, and development - 1 Jan 2009
Parry Laura J, Vodstrcil Lenka A, Madden Anna, Amir Stephanie H, Baldwin Katrina, Wlodek Mary E, Nicholas Kevin R
Abstract excerpt
Pups born to mice with a targeted deletion of relaxin or its receptor (Rxfp1) die within 24 h postpartum. This has been attributed, in part, to abnormal mammary gland development in relaxin-mutant mice (Rln-/-). However, mammary development is normal in relaxin receptor-mutant (Rxfp1-/-) mice. The present study aimed to verify the mammary phenotypes in late pregnant and early lactating Rln-/- mice and to test the...
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