Article
GREAT/LGR8 is the only receptor for insulin-like 3 peptide.
Molecular endocrinology (Baltimore, Md.) - 1 Dec 2003
Bogatcheva Natalia V, Truong Anne, Feng Shu, Engel Wolfgang, Adham Ibrahim M, Agoulnik Alexander I
Abstract excerpt
During male development testes descend from their embryonic intraabdominal position into the scrotum. Two genes, encoding the insulin-like 3 peptide (INSL3) and the GREAT/LGR8 G protein-coupled receptor, control the differentiation of gubernaculum, the caudal genitoinguinal ligament critical for...
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