Article
Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases.
Human molecular genetics - 15 Sept 2004
Ghosh Srimoyee, Feany Mel B
Abstract excerpt
Most human neurodegenerative diseases have a number of common features, including adult onset, progressive degeneration of selected neuronal populations and formation of abnormal protein aggregates. Although these shared characteristics raise the possibility of conserved pathogenic mechanisms, the diverse clinical and pathological features of each disorder indicate significant differences. As a number of human...
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