Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modelling neurodegenerative diseases in Drosophila: a fruitful approach?

Nature reviews. Neuroscience - 1 Mar 2002

Muqit Miratul M K, Feany Mel B

Abstract excerpt

Human neurodegenerative diseases are characterized by the progressive loss of specific neuronal populations, resulting in substantial disability and early death. The identification of causative single-gene mutations in families with inherited neurodegenerative disorders has facilitated the modelling of these diseases in experimental organisms, including the fruitfly Drosophila melanogaster. Many neurodegenerative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Animals, Genetically Modified
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Mutation

Share to Neurodegenerative Diseases

Share to Parkinson Disease

Share to Trinucleotide Repeat Expansion

Source

Identifiers

PMID: 11994755
DOI: 10.1038/nrn751

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modelling neurodegenerative diseases in Drosophila: a fruitful approach?PMID 11994755Read ↗

Drosophila models of neurodegenerative diseases.Semantic proximity Read ↗

Drosophila models of neurodegenerative diseaseSemantic proximity Read ↗

Drosophila melanogaster in the Study of Human NeurodegenerationSemantic proximity Read ↗

Drosophila: a "model" model system to study neurodegeneration.Semantic proximity Read ↗

Studies of neurodegenerative diseases using Drosophila and the development of novel approaches for their analysisSemantic proximity Read ↗

Modeling Neurodegenerative Disorders in Drosophila melanogaster.Semantic proximity Read ↗

Modeling Parkinson’s Disease in Drosophila: What Have We Learned for Dominant Traits?Semantic proximity Read ↗

<i>Drosophila</i> as an <i>In Vivo</i> Model for Human Neurodegenerative DiseaseSemantic proximity Read ↗

Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants.Semantic proximity Read ↗

Neurodegenerative mutants in Drosophila: a means to identify genes and mechanisms involved in human diseases?Semantic proximity Read ↗

Drosophila Models of Human DiseaseSemantic proximity Read ↗

Drosophila Models of Parkinson's Disease: Discovering Relevant Pathways and Novel Therapeutic StrategiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.